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・ 7,N,N-TMT
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・ 7-Aminoactinomycin D
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・ 7-carboxy-7-deazaguanine synthase
・ 7-Chloro-L-tryptophan oxidase
・ 7-Chlorokynurenic acid
・ 7-cube
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・ 7-day SEC yield
・ 7-Dehydrocholesterol
7-Dehydrocholesterol reductase
・ 7-Dehydrodesmosterol
・ 7-Dehydrositosterol
・ 7-demicube
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・ 7-Deoxyloganetic acid
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・ 7-epi-alpha-selinene synthase


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7-Dehydrocholesterol reductase : ウィキペディア英語版
7-Dehydrocholesterol reductase

7-dehydrocholesterol reductase, also known as DHCR7, is a protein that in humans is encoded by the ''DHCR7'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1717 )
==Function==

The protein encoded by this gene is an enzyme catalyzing the production of cholesterol from 7-Dehydrocholesterol using NADPH.
The DHCR7 gene encodes delta-7-sterol reductase (EC 1.3.1.21), the ultimate enzyme of mammalian sterol biosynthesis that converts 7-dehydrocholesterol (7-DHC) to cholesterol. This enzyme removes the C(7-8) double bond introduced by the sterol delta8-delta7 isomerases. In addition, its role in drug-induced malformations is known: inhibitors of the last step of cholesterol biosynthesis such as AY9944 and BM15766 severely impair brain development.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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